9 Symptoms Men Should Never Ignore

2. Toe Pain

In the vast majority of cases the big toe is going to be where this problem manifests. A pesky and potentially painful condition called gout could be the culprit, and since it is three or four times as likely to happen to men than it is to women, men should pay particularly close attention to this symptom. Gout happens when too much uric acid builds up in the blood stream and causes tiny crystals of sodium urate to collect around joints. The longer gout goes untreated, the worse it is likely to get and sometimes it can result in permanent damage to joints.