5. Poor circulation

Image Source: State Farm
Poor blood circulation is another hazard linked to sitting for long periods of time. When this happens, legs can begin to retain fluid, and potentially lead to conditions such as varicose veins, swollen ankles and even something known as deep-vein thrombosis or DVT, which can result in the formation of clots in the legs which may then travel to other areas of the body like the heart and lungs, causing a life-threatening medical emergency.